Background Monoclonal antibodies (mAbs), as a class of precision-targeted immunoglobulins (Ig), consist of an antigen-binding region (F(ab')₂) and an effector function region (Fc). In terms of m...
Introduction In the field of autoimmune disease treatment, TL1A (TNF-like ligand 1A) and its receptors DR3 (Death Receptor 3) and decoy receptor DcR3 (Decoy Receptor 3) have emerged as promising new ...
In our previous issue, we introduced VKEY-BIO's new TR-FRET Effector Function Analysis Kits (CD16a/CD64) to aid in the assessment of antibody ADCC/ADCP functions. This issue focuses on another cor...
The Challenges and Breakthroughs in Hybridoma ScreeningIn monoclonal antibody development, hybridoma screening is a critical bottleneck. Traditional methods (like ELISA) are time-consuming (often requ...
Cyclic adenosine monophosphate (cAMP) is a crucial intracellular second messenger involved in regulating various physiological processes, such as metabolism, secretion, and gene expression. In drug de...
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