Using the KeyTec® TR - FRET technology for high - throughput screening of small - molecule inhibitors, polypeptides or antibody blockers has the characteristics of simplicity, rapidity and high accuracy.
![KeyTec® TR-FRET GDP loaded KRAS[G12D]/SOS1 Binding Assay kit](/themes/simple/img1/i-right.svg "KeyTec® TR-FRET GDP loaded KRAS[G12D]/SOS1 Binding Assay kit"){kind=small}
The KeyTec® TR-FRET GDP loaded KRAS[G12D]/SOS1 Binding Assay kit is designed for measurement of the interaction between KRAS[G12D] and SOS1 proteins. It is based on sandwich immunoassay model and utilizes TR-FRET technology, known for its ease of use, homogeneity (no wash), low background, high sensitivity, high accuracy.
KeyTec® TR-FRET PD1/PD-L1 Binding Assay Kit is designed for the quantitative measurement of the interaction between human PD1 and PD-L1 proteins. This kit provides a Tag1-PD-L1 protein, a Tag2-PD1 protein, an anti-tag1 antibody labeled with KeyTec® TR-FRET Solar Eu* 1 (mAb anti-Tag1 - Solar Eu) ,an anti-tag2 antibody labeled with KeyTec® TR-FRET LA* 2 (mAb anti-Tag2 - LA) and other detection reagents. These components enable the high-throughput screening of small molecule inhibitors, peptides, or antibody blockers.
KeyTec® TR-FRET human cereblon binding kit is designed for the binding analysis of cereblon ligands/inhibitors to wild-type human cereblon.
KeyTec® TR-FRET human von Hippel−Lindau(VHL) binding kit is designed for the binding analysis of VHL ligands/inhibitors to wild-type human VHL. This assay is based on a competitive immunoassay method using KeyTec® TR-FRET technology, offering a simple, rapid, highly specific and sensitive, as well as reproducible detection process.
KeyTec® TR-FRET Human PARG Inhibitor Screening Kit is designed for screening inhibitors of the PARG enzyme. This kit employs an immunoassay developed using KeyTec® TR-FRET technology, featuring simplicity, speed, high accuracy, and excellent reproducibility.
KeyTec® TR-FRET STAT6 / CRBN PROTAC Binding Assay Kit can be used to screen PROTAC molecules that mediate the formation of a ternary complex between STAT6 protein and the CRBN/DDB1 complex. This kit is a binding immunoassay developed using KeyTec® TR-FRET technology, featuring simplicity, speed, high accuracy, and excellent reproducibility.
KeyTec® TR-FRET Human STING WT Protein Binding Assay Kit can be used to measure the binding of ligands or inhibitors to wild-type human STING protein. This kit is a competitive immunoassay developed using KeyTec® TR-FRET technology, featuring simplicity, speed, high specificity, high sensitivity, and excellent reproducibility.
KeyTec® TR-FRET BTK WT / CRBN PROTAC Binding Assay Kit can be used to screen PROTAC molecules that mediate the formation of a ternary complex between wild-type BTK protein and the CRBN/DDB1 complex. This kit is a binding immunoassay developed using KeyTec® TR-FRET technology, featuring simplicity, speed, high accuracy, and excellent reproducibility.
KeyTec® TR-FRET BRD4 / VHL PROTAC Binding Assay Kit can be used to screen PROTAC molecules that mediate the formation of a ternary complex between BRD4 protein and the VHL/Elongin C/Elongin B protein complex (VHL/Elongin C/Elongin B protein complex, hereinafter referred to as the VCB complex).
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