The polyhistidine tag (His tag) is the most prevalent affinity tag in recombinant protein research and the biotechnology field. Typically composed of six or more consecutive histidine residues fused t...
Recently, the Shanghai Municipal Commission of Economy and Informatization officially released the "2025 List of Shanghai Specialized and Sophisticated SMEs (Fourth Batch)". VKEY-BIO (Shangh...
BACKGROUNDIn the field of drug discovery, Signal Transducer and Activator of Transcription 6 (STAT6) has long been a challenging "undruggable" target for countless scientists. As the core do...
The cyclic GMP-AMP synthase (cGAS)–stimulator of interferon genes (STING) signaling pathway is a cytosolic DNA-sensing pathway that plays a crucial role in innate immune responses. When cGAS recogniz...
BackgroundIn the field of targeted cancer therapy, PROTAC (Proteolysis-Targeting Chimera) technology is leading a revolutionary paradigm shift. Unlike traditional small molecule inhibitors, PROTAC mol...
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