During the cell's life cycle, cells can be subject to different types of exogenous and endogenous damages.
In order to survive under these adverse conditions and transmit complete genetic information to their offspring, cells have formed a complex network of signaling pathways, collectively known as the DNA damage response (DDR). The DDR is the core mechanism by which cells detect, respond to, and repair DNA damage.
KeyTec® WRN, N-His; C-Flag M1-S1432(end) is a recombinant protein with a 6X His tag at the N-terminus and a Flag tag at the C-terminus. The protein was purified using Ni-NTA affinity chromatography. This WRN protein batch has high enzymatic activity in the ADP-Glo assay.
A strict QC (quality control) test report is provided for each batch.
Each batch has been verified for enzyme activity.
Verified by common homogeneous methods such as TR-FRET, Luminescence and fluorescence.
High-performance at competitive prices.
For KeyTec® protein products, each batch of protein is subjected to a series of rigorous validation procedures to obtain data such as purity, monomer/polymer morphology, enzyme activity information, positive compound validation information, and so forth.
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